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Protein Unfolding by SDS: the Microscopic Mechanisms and the Properties of the SDS-Protein Assembly()

The effects of detergent sodium dodecyl sulfate (SDS) on protein structure and dynamics are fundamental to the most common laboratory technique used to separate proteins and determine their molecular weights: polyacrylamide gel electrophoresis. However, the mechanism by which SDS induces protein unf...

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Publicado en:Nanoscale
Main Authors: Winogradoff, David, John, Shalini, Aksimentiev, Aleksei
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7291819/
https://ncbi.nlm.nih.gov/pubmed/32080694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9nr09135a
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