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Sparsity-Penalized Stacked Denoising Autoencoders for Imputing Single-Cell RNA-seq Data

Single-cell RNA-seq (scRNA-seq) is quite prevalent in studying transcriptomes, but it suffers from excessive zeros, some of which are true, but others are false. False zeros, which can be seen as missing data, obstruct the downstream analysis of single-cell RNA-seq data. How to distinguish true zero...

詳細記述

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書誌詳細
出版年:Genes (Basel)
主要な著者: Chi, Weilai, Deng, Minghua
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7291078/
https://ncbi.nlm.nih.gov/pubmed/32403260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes11050532
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