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Cytotoxic 4-Hydroxyprorocentrolide and Prorocentrolide C from Cultured Dinoflagellate Prorocentrum lima Induce Human Cancer Cell Death through Apoptosis and Cell Cycle Arrest

Prorocentrolide and its analogs, the novel naturally derived antitumor agents, have recently been identified in the dinoflagellate Prorocentrum lima. In the current study, the underlying inhibitory mechanisms of 4-hydroxyprorocentrolide (1) and prorocentrolide C (2) on the proliferation of human car...

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Detalles Bibliográficos
Publicado en:Toxins (Basel)
Main Authors: Lee, Seon Min, Kim, Na-Hyun, Jeong, Eun Ju, Rho, Jung-Rae
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7290926/
https://ncbi.nlm.nih.gov/pubmed/32392799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins12050304
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