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Cytotoxic 4-Hydroxyprorocentrolide and Prorocentrolide C from Cultured Dinoflagellate Prorocentrum lima Induce Human Cancer Cell Death through Apoptosis and Cell Cycle Arrest

Prorocentrolide and its analogs, the novel naturally derived antitumor agents, have recently been identified in the dinoflagellate Prorocentrum lima. In the current study, the underlying inhibitory mechanisms of 4-hydroxyprorocentrolide (1) and prorocentrolide C (2) on the proliferation of human car...

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Bibliografske podrobnosti
izdano v:Toxins (Basel)
Main Authors: Lee, Seon Min, Kim, Na-Hyun, Jeong, Eun Ju, Rho, Jung-Rae
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7290926/
https://ncbi.nlm.nih.gov/pubmed/32392799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins12050304
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