Multi-Omics Analysis of Diabetic Heart Disease in the db/db Model Reveals Potential Targets for Treatment by a Longevity-Associated Gene

Characterisation of animal models of diabetic cardiomyopathy may help unravel new molecular targets for therapy. Long-living individuals are protected from the adverse influence of diabetes on the heart, and the transfer of a longevity-associated variant (LAV) of the human BPIFB4 gene protects cardi...

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Publicado en:Cells
Main Authors: Faulkner, Ashton, Dang, Zexu, Avolio, Elisa, Thomas, Anita C, Batstone, Thomas, Lloyd, Gavin R, Weber, Ralf JM, Najdekr, Lukáš, Jankevics, Andris, Dunn, Warwick B, Spinetti, Gaia, Vecchione, Carmine, Puca, Annibale A, Madeddu, Paolo
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7290798/
https://ncbi.nlm.nih.gov/pubmed/32455800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9051283
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