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Asiaticoside attenuates neonatal hypoxic–ischemic brain damage through inhibiting TLR4/NF-κB/STAT3 pathway

BACKGROUND: Neonatal hypoxic ischemic encephalopathy (HIE) is currently a leading cause of neonatal death. Asiaticoside (AT), a bioactive constituent isolated from Centella asiatica, possesses numerous biological properties. For instance, previous studies showed that AT could protect ischemia hypoxi...

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Bibliographic Details
Published in:Ann Transl Med
Main Authors: Zhou, Yu, Wang, Si, Zhao, Jing, Fang, Ping
Format: Artigo
Language:Inglês
Published: AME Publishing Company 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7290617/
https://ncbi.nlm.nih.gov/pubmed/32566578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm-20-3323
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