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ROCK (RhoA/Rho Kinase) in Cardiovascular–Renal Pathophysiology: A Review of New Advancements

Rho-associated, coiled-coil containing kinases (ROCK) were originally identified as effectors of the RhoA small GTPase and found to belong to the AGC family of serine/threonine kinases. They were shown to be downstream effectors of RhoA and RhoC activation. They signal via phosphorylation of protein...

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Detalhes bibliográficos
Publicado no:J Clin Med
Main Authors: Seccia, Teresa M., Rigato, Matteo, Ravarotto, Verdiana, Calò, Lorenzo A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7290501/
https://ncbi.nlm.nih.gov/pubmed/32370294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm9051328
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