Secretome of Mesenchymal Stromal Cells Prevents Myofibroblasts Differentiation by Transferring Fibrosis-Associated microRNAs within Extracellular Vesicles

Fibroblasts differentiation into myofibroblasts is a central event of tissue fibrosis. Multipotent mesenchymal stromal cells (MSCs) secretome can interfere with fibrosis development; despite precise underlying mechanisms remain unclear. In this study, we tested the hypothesis that MSC secretome can...

Full description

Saved in:
Bibliographic Details
Published in:Cells
Main Authors: Basalova, Nataliya, Sagaradze, Georgy, Arbatskiy, Mikhail, Evtushenko, Evgeniy, Kulebyakin, Konstantin, Grigorieva, Olga, Akopyan, Zhanna, Kalinina, Natalia, Efimenko, Anastasia
Format: Artigo
Language:Inglês
Published: MDPI 2020
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7290371/
https://ncbi.nlm.nih.gov/pubmed/32443855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9051272
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items