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Association between low body weight and cytochrome P‐450 enzyme activity in patients with anorexia nervosa

Very little is known to which extent severe underweight could affect cytochrome P‐450 (CYP) enzyme activity. In this study, 24 patients with anorexia nervosa at two occasions ingested single oral doses of five test drugs known to be metabolized by CYP1A2, CYP2C9, CYP2C19, CYP2D6, and CYP3A4, respect...

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Dettagli Bibliografici
Pubblicato in:Pharmacol Res Perspect
Autori principali: Sandvik, Pål, Lydersen, Stian, Hegstad, Solfrid, Spigset, Olav
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7290083/
https://ncbi.nlm.nih.gov/pubmed/32529756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.615
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