Histologic Subtypes and Response to PD-1/PD-L1 Blockade in Advanced Urothelial Cancer: A Retrospective Study

PURPOSE: Urinary tract cancer can be pure urothelial carcinoma (PUC), pure non-UC, or variant UC (VUC, defined here as mixed UC). Little is known regarding outcomes for patients with VUC receiving immune checkpoint inhibitors (ICI). We hypothesized that VUC does not compromise ICI efficacy in patien...

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Veröffentlicht in:J Urol
Hauptverfasser: Miller, Natalie J, Khaki, Ali Raza, Diamantopoulos, Leonidas N, Bilen, Mehmet A, Santos, Victor, Agarwal, Neeraj, Morales-Barrera, Rafael, Devitt, Michael, Nelson, Ariel, Hoimes, Christopher J, Shreck, Evan, Assi, Hussein, Gartrell, Benjamin A, Sankin, Alex, Rodriguez-Vida, Alejo, Lythgoe, Mark, Pinato, David J, Drakaki, Alexandra, Joshi, Monika, Isaacsson Velho, Pedro, Hahn, Noah, Liu, Sandy, Alonso Buznego, Lucia, Duran, Ignacio, Moses, Marcus, Jain, Jayanshu, Murgic, Jure, Barata, Pedro, Tripathi, Abhishek, Zakharia, Yousef, Galsky, Matthew D, Sonpavde, Guru, Yu, Evan Y, Lyman, Gary H, Grivas, Petros
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7289665/
https://ncbi.nlm.nih.gov/pubmed/31971495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JU.0000000000000761
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