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Mesenchymal traits at the convergence of tumor-intrinsic and -extrinsic mechanisms of resistance to immune checkpoint blockers

Targeting of immune checkpoint blockers (ICBs), such as cytotoxic T-lymphocyte antigen-4 and programmed-death 1/programmed-death ligand 1, has dramatically changed the landscape of cancer treatment. Seeing patients who were refractory to conventional therapy recover after immunotherapy, with high ra...

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Détails bibliographiques
Publié dans:Emerg Top Life Sci
Auteurs principaux: Trono, Paola, Sistigu, Antonella, Palermo, Belinda, Ciliberto, Gennaro, Nisticò, Paola
Format: Artigo
Langue:Inglês
Publié: Portland Press Ltd. 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7289012/
https://ncbi.nlm.nih.gov/pubmed/33525801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/ETLS20170068
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