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Genome editing for blood disorders: state of the art and recent advances

In recent years, tremendous advances have been made in the use of gene editing to precisely engineer the genome. This technology relies on the activity of a wide range of nuclease platforms — such as zinc-finger nucleases, transcription activator-like effector nucleases, and the CRISPR–Cas system —...

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Detalhes bibliográficos
Publicado no:Emerg Top Life Sci
Main Authors: Romito, Marianna, Rai, Rajeev, Thrasher, Adrian J., Cavazza, Alessia
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7288986/
https://ncbi.nlm.nih.gov/pubmed/33523137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/ETLS20180147
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