Topoisomerase II-binding protein 1 promotes the progression of prostate cancer via ATR-CHK1 signaling pathway

DNA damage response (DDR) plays an important role in the progression of cancers, including prostate cancer (PCa). Topoisomerase II-binding protein 1 (TopBP1) is an essential promotor of ATR-mediated DDR. Herein, we investigated the association between TopBP1 and PCa and determined its effect on the...

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Enregistré dans:
Détails bibliographiques
Publié dans:Aging (Albany NY)
Auteurs principaux: Li, Kaiwen, Peng, Shirong, Li, Zean, Lai, Yiming, Wang, Qiong, Tao, Yiran, Wu, Wanhua, Zhou, Qianghua, Gao, Ze, Chen, Junxiu, Li, Hui, Cai, Wenli, Guo, Zhenghui, Huang, Hai
Format: Artigo
Langue:Inglês
Publié: Impact Journals 2020
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7288942/
https://ncbi.nlm.nih.gov/pubmed/32459662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103260
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