A new modeling and inference approach for the Systolic Blood Pressure Intervention Trial outcomes

BACKGROUND/AIMS: In clinical trials with time-to-event outcomes, usually the significance tests and confidence intervals are based on a proportional hazards model. Thus, the temporal pattern of the treatment effect is not directly considered. This could be problematic if the proportional hazards ass...

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Pubblicato in:Clin Trials
Autori principali: Yang, Song, Ambrosius, Walter T, Fine, Lawrence J, Bress, Adam P, Cushman, William C, Raj, Dominic S, Rehman, Shakaib, Tamariz, Leonardo
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7288219/
https://ncbi.nlm.nih.gov/pubmed/29671345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1740774518769865
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