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1,2,4-Triazine Sulfonamides: Synthesis by Sulfenamide Intermediates, In Vitro Anticancer Screening, Structural Characterization, and Molecular Docking Study

In this study, we synthesized novel sulfonamides with a 1,2,4-triazine moiety according to pharmacophore requirements for biological activity. All the synthesized compounds were tested in vitro to verify whether they exhibited anticancer activity against the human breast cancer cell lines MCF-7 and...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Branowska, Danuta, Karczmarzyk, Zbigniew, Wolińska, Ewa, Wysocki, Waldemar, Morawiak, Maja, Urbańczyk-Lipkowska, Zofia, Bielawska, Anna, Bielawski, Krzysztof
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7288137/
https://ncbi.nlm.nih.gov/pubmed/32429377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25102324
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