Virtual Screening and the In Vitro Assessment of the Antileishmanial Activity of Lignans

Leishmaniasis is endemic in at least 98 countries. Due to the high toxicity and resistance associated with the drugs, we chose lignans as an alternative, due to their favorable properties of absorption, distribution, metabolism, excretion, and toxicity (ADMET). To investigate their leishmanicidal po...

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Publicado en:Molecules
Autores principales: dos Santos Maia, Mayara, Raimundo e Silva, Joanda Paolla, de Lima Nunes, Thaís Amanda, Saraiva de Sousa, Julyanne Maria, Soares Rodrigues, Gabriela Cristina, Messias Monteiro, Alex France, Fechine Tavares, Josean, da Franca Rodrigues, Klinger Antonio, B. Mendonça-Junior, Francisco Jaime, Scotti, Luciana, Scotti, Marcus Tullius
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7288103/
https://ncbi.nlm.nih.gov/pubmed/32408657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25102281
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