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Chiral Phase Transfer Catalysis in the Asymmetric Synthesis of a 3,3-Disubstituted Isoindolinone and Determination of Its Absolute Configuration by VCD Spectroscopy

In this work we report our endeavors toward the development of an asymmetric synthesis of a 3,3-disubstituted isoindolinone, dimethyl 2-(1-methyl-3-oxoisoindolin-1-yl)malonate, via asymmetric cascade reaction of 2-acetylbenzonitrile with dimethylmalonate and the determination of its absolute configu...

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Bibliografske podrobnosti
izdano v:Molecules
Main Authors: Monaco, Guglielmo, Tiffner, Maximilian, Mola, Antonia Di, Herrebout, Wouter, Waser, Mario, Massa, Antonio
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7287911/
https://ncbi.nlm.nih.gov/pubmed/32408552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25102272
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