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N-Alkyl-2-[4-(trifluoromethyl)benzoyl]hydrazine-1-carboxamides and Their Analogues: Synthesis and Multitarget Biological Activity

Based on the isosterism concept, we have designed and synthesized homologous N-alkyl-2-[4-(trifluoromethyl)benzoyl]hydrazine-1-carboxamides (from C(1) to C(18)) as potential antimicrobial agents and enzyme inhibitors. They were obtained from 4-(trifluoromethyl)benzohydrazide by three synthetic appro...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Krátký, Martin, Baranyai, Zsuzsa, Štěpánková, Šárka, Svrčková, Katarína, Švarcová, Markéta, Stolaříková, Jiřina, Horváth, Lilla, Bősze, Szilvia, Vinšová, Jarmila
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7287908/
https://ncbi.nlm.nih.gov/pubmed/32408517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25102268
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