Topical VEGF-C/D Inhibition Prevents Lymphatic Vessel Ingrowth into Cornea but Does Not Improve Corneal Graft Survival

Vascular endothelial growth factor-C/D (VEGF-C/D) regulates lymphangiogenesis. Ingrowth of lymphatic vessels is negatively associated with corneal transplantation success. In this study, we therefore analyzed the effect local blockade of VEGF-C/D has on inflamed corneas. We used the murine model of...

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Detalhes bibliográficos
Publicado no:J Clin Med
Main Authors: Salabarria, Ann-Charlott, Koch, Manuel, Schönberg, Alfrun, Zinser, Elisabeth, Hos, Deniz, Hamdorf, Matthias, Imhof, Thomas, Braun, Gabriele, Cursiefen, Claus, Bock, Felix
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7287580/
https://ncbi.nlm.nih.gov/pubmed/32353986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm9051270
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