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Curcumin blunts epithelial-mesenchymal transition of hepatocytes to alleviate hepatic fibrosis through regulating oxidative stress and autophagy

The massive production and activation of myofibroblasts (MFB) is key to the development of liver fibrosis. In many studies, it has been proven that hepatocytes are an important part of MFB, and can be transformed into MFB through epithelial-mesenchymal transition (EMT) during hepatic fibrogenesis. I...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Kong, Desong, Zhang, Zili, Chen, Liping, Huang, Weifang, Zhang, Feng, Wang, Ling, Wang, Yu, Cao, Peng, Zheng, Shizhong
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7287144/
https://ncbi.nlm.nih.gov/pubmed/32526690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101600
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