Therapeutic targeting of p300/CBP HAT domain for the treatment of NUT midline carcinoma

Nuclear protein of the testis (NUT) midline carcinoma (NMC), is a rare and highly aggressive form of undifferentiated squamous cell carcinoma. NMC is molecularly characterized by chromosomal rearrangement of the NUT gene to another gene, most commonly the bromodomain and extraterminal domain (BET) g...

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Библиографические подробности
Опубликовано в: :Oncogene
Главные авторы: Zhang, Xin, Zegar, Tim, Lucas, Anais, Morrison-Smith, Chevaun, Knox, Tatiana, French, Christopher A., Knapp, Stefan, Müller, Susanne, Siveke, Jens T.
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2020
Предметы:
Brief Communication
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7286816/
https://ncbi.nlm.nih.gov/pubmed/32366905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-1301-9
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