Reprogramming of Lipid Metabolism as a New Driving Force Behind Tauroursodeoxycholic Acid-Induced Neural Stem Cell Proliferation

Recent evidence suggests that neural stem cell (NSC) fate is highly dependent on mitochondrial bioenergetics. Tauroursodeoxycholic acid (TUDCA), an endogenous neuroprotective bile acid and a metabolic regulator, stimulates NSC proliferation and enhances adult NSC pool in vitro and in vivo. In this s...

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Vydáno v:Front Cell Dev Biol
Hlavní autoři: Fernandes, Marta B., Costa, Márcia, Ribeiro, Maria Filipe, Siquenique, Sónia, Sá Santos, Sónia, Martins, Joana, Coelho, Ana V., Silva, Margarida F. B., Rodrigues, Cecília M. P., Solá, Susana
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Cell and Developmental Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7286385/
https://ncbi.nlm.nih.gov/pubmed/32582686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00335
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