TMPRSS2 and TMPRSS4 promote SARS-CoV-2 infection of human small intestinal enterocytes

Gastrointestinal symptoms and fecal shedding of SARS-CoV-2 RNA are frequently observed in COVID-19 patients. However, it is unclear whether SARS-CoV-2 replicates in the human intestine and contributes to possible fecal-oral transmission. Here, we report productive infection of SARS-CoV-2 in ACE2(+)...

詳細記述

保存先:
書誌詳細
出版年:Sci Immunol
主要な著者: Zang, Ruochen, Gomez Castro, Maria Florencia, McCune, Broc T., Zeng, Qiru, Rothlauf, Paul W., Sonnek, Naomi M., Liu, Zhuoming, Brulois, Kevin F., Wang, Xin, Greenberg, Harry B., Diamond, Michael S., Ciorba, Matthew A., Whelan, Sean P. J., Ding, Siyuan
フォーマット: Artigo
言語:Inglês
出版事項: American Association for the Advancement of Science 2020
主題:
Research Articles
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7285829/
https://ncbi.nlm.nih.gov/pubmed/32404436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.abc3582
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