LGR5 in breast cancer and ductal carcinoma in situ: a diagnostic and prognostic biomarker and a therapeutic target

BACKGROUND: Novel biomarkers are required to discern between breast tumors that should be targeted for treatment from those that would never become clinically apparent and/or life threatening for patients. Moreover, therapeutics that specifically target breast cancer (BC) cells with tumor-initiating...

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Vydáno v:BMC Cancer
Hlavní autoři: Hagerling, Catharina, Owyong, Mark, Sitarama, Vaishnavi, Wang, Chih-Yang, Lin, Charlene, van den Bijgaart, Renske J. E., Koopman, Charlotte D., Brenot, Audrey, Nanjaraj, Ankitha, Wärnberg, Fredrik, Jirström, Karin, Klein, Ophir D., Werb, Zena, Plaks, Vicki
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7285764/
https://ncbi.nlm.nih.gov/pubmed/32522170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-06986-z
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