LAT1 (SLC7A5) and CD98hc (SLC3A2) complex dynamics revealed by single-particle cryo-EM

Solute carriers are a large class of transporters that play key roles in normal and disease physiology. Among the solute carriers, heteromeric amino-acid transporters (HATs) are unique in their quaternary structure. LAT1–CD98hc, a HAT, transports essential amino acids and drugs across the blood–brai...

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Publicat a:Acta Crystallogr D Struct Biol
Autors principals: Chiduza, George N., Johnson, Rachel M., Wright, Gareth S. A., Antonyuk, Svetlana V., Muench, Stephen P., Hasnain, S. Samar
Format: Artigo
Idioma:Inglês
Publicat: International Union of Crystallography 2019
Matèries:
Research Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7285653/
https://ncbi.nlm.nih.gov/pubmed/31282475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2059798319009094
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