Apple Flavonols Mitigate Adipocyte Inflammation and Promote Angiogenic Factors in LPS- and Cobalt Chloride-Stimulated Adipocytes, in Part by a Peroxisome Proliferator-Activated Receptor-γ-Dependent Mechanism

Adipose tissue (AT) expansion induces local hypoxia, a key contributor to the chronic low-grade inflammation that drives obesity-associated disease. Apple flavonols phloretin (PT) and phlorizin (PZ) are suggested anti-inflammatory molecules but their effectiveness in obese AT is inadequately underst...

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Detalhes bibliográficos
Publicado no:Nutrients
Main Authors: Liddle, Danyelle M., Kavanagh, Meaghan E., Wright, Amanda J., Robinson, Lindsay E.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7284758/
https://ncbi.nlm.nih.gov/pubmed/32408695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu12051386
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