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Neuroprotective Effect of Ropinirole Lipid Nanoparticles Enriched Hydrogel for Parkinson’s Disease: In Vitro, Ex Vivo, Pharmacokinetic and Pharmacodynamic Evaluation

Parkinson’s disease (rp) is a progressive neurodegenerative disorder. Ropinirole (RP) is a newer generation dopamine agonist used for the treatment of PD. It is prescribed as oral dosage form. However, limited oral bioavailability and frequent dosing limits the RP usage. The objective of the current...

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Bibliographic Details
Published in:Pharmaceutics
Main Authors: Dudhipala, Narendar, Gorre, Thirupathi
Format: Artigo
Language:Inglês
Published: MDPI 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7284436/
https://ncbi.nlm.nih.gov/pubmed/32414195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12050448
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