First comprehensive computational analysis of functional consequences of TMPRSS2 SNPs in susceptibility to SARS-CoV-2 among different populations

Current SARS-CoV-2 pandemy mortality created the hypothesis that some populations may be more susceptible to SARS-CoV-2. TMPRSS2 encodes a transmembrane serine protease which plays a crucial role in SARS-CoV-2 cell entry. Single nucleotide polymorphisms (SNPs) in TMPRSS2 might influence SARS-CoV2 en...

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Vydáno v:J Biomol Struct Dyn
Hlavní autoři: Paniri, Alireza, Hosseini, Mohammad Mahdi, Akhavan-Niaki, Haleh
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2020
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7284145/
https://ncbi.nlm.nih.gov/pubmed/32410502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/07391102.2020.1767690
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