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Microscale Collagen and Fibroblast Interactions Enhance Primary Human Hepatocyte Functions in Three-Dimensional Models

Human liver models that are three-dimensional (3D) in architecture are indispensable for compound metabolism/toxicity screening, to model liver diseases for drug discovery, and for cell-based therapies; however, further development of such models is needed to maintain high levels of primary human he...

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Vydáno v:Gene Expr
Hlavní autoři: Kukla, David A., Crampton, Alexandra L., Wood, David K., Khetani, Salman R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cognizant Communication Corporation 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7284102/
https://ncbi.nlm.nih.gov/pubmed/32290899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3727/105221620X15868728381608
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