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Ocular Tolerability and Immune Response to Corneal Intrastromal AAV-IDUA Gene Therapy in New Zealand White Rabbits
The chronic ocular toxicity, tolerability, and inflammation following corneal intrastromal injection of saline or escalating doses of an adeno-associated virus (AAV) containing a codon-optimized α-l-iduronidase (AAV-opt-IDUA) expression cassette were evaluated in New Zealand White rabbits. Corneal o...
Tallennettuna:
| Julkaisussa: | Mol Ther Methods Clin Dev |
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| Päätekijät: | , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Society of Gene & Cell Therapy
2020
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7284066/ https://ncbi.nlm.nih.gov/pubmed/32542182 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2020.05.014 |
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