Epigenetic Marks at the Ribosomal DNA Promoter in Skeletal Muscle Are Negatively Associated With Degree of Impairment in Cerebral Palsy

Introduction: Cerebral palsy (CP) is the most common motor impairment in children. Skeletal muscles in individuals with CP are typically weak, thin, and stiff. Whether epigenetic changes at the ribosomal DNA (rDNA) promoter are involved in this dysregulation remains unknown. Methods: Skeletal muscle...

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Vydáno v:Front Pediatr
Hlavní autoři: von Walden, Ferdinand, Fernandez-Gonzalo, Rodrigo, Pingel, Jessica, McCarthy, John, Stål, Per, Pontén, Eva
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Pediatrics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7283884/
https://ncbi.nlm.nih.gov/pubmed/32582584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fped.2020.00236
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