Long-Term Neuroanatomical Consequences of Childhood Maltreatment: Reduced Amygdala Inhibition by Medial Prefrontal Cortex

Similar to patients with Major depressive disorder (MDD), healthy subjects at risk for depression show hyperactivation of the amygdala as a response to negative emotional expressions. The medial prefrontal cortex is responsible for amygdala control. Analyzing a large cohort of healthy subjects, we a...

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Pubblicato in:Front Syst Neurosci
Autori principali: Kessler, Roman, Schmitt, Simon, Sauder, Torsten, Stein, Frederike, Yüksel, Dilara, Grotegerd, Dominik, Dannlowski, Udo, Hahn, Tim, Dempfle, Astrid, Sommer, Jens, Steinsträter, Olaf, Nenadic, Igor, Kircher, Tilo, Jansen, Andreas
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
Soggetti:
Neuroscience
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7283497/
https://ncbi.nlm.nih.gov/pubmed/32581732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnsys.2020.00028
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