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An anticonvulsive drug, valproic acid (valproate), has effects on the biosynthesis of fatty acids and polyketides in microorganisms

Valproic acid or valproate (VPA) is an anticonvulsive drug used for treatments of epilepsy, bipolar disorder, and migraine headaches. VPA is also an epigenetic modulator, inhibiting histone deacetylase, and it has been subjected to clinical study for cancer treatment. During the investigation of VPA...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Poolchanuan, Prapassorn, Unagul, Panida, Thongnest, Sanit, Wiyakrutta, Suthep, Ngamrojanavanich, Nattaya, Mahidol, Chulabhorn, Ruchirawat, Somsak, Kittakoop, Prasat
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7283484/
https://ncbi.nlm.nih.gov/pubmed/32518288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-66251-y
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