Restriction of essential amino acids dictates the systemic metabolic response to dietary protein dilution

Dietary protein dilution (DPD) promotes metabolic-remodelling and -health but the precise nutritional components driving this response remain elusive. Here, by mimicking amino acid (AA) supply from a casein-based diet, we demonstrate that restriction of dietary essential AA (EAA), but not non-EAA, d...

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Udgivet i:Nat Commun
Main Authors: Yap, Yann W., Rusu, Patricia M., Chan, Andrea Y., Fam, Barbara C., Jungmann, Andreas, Solon-Biet, Samantha M., Barlow, Christopher K., Creek, Darren J., Huang, Cheng, Schittenhelm, Ralf B., Morgan, Bruce, Schmoll, Dieter, Kiens, Bente, Piper, Matthew D. W., Heikenwälder, Mathias, Simpson, Stephen J., Bröer, Stefan, Andrikopoulos, Sofianos, Müller, Oliver J., Rose, Adam J.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7283339/
https://ncbi.nlm.nih.gov/pubmed/32518324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16568-z
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