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Haplotype Analysis in Carriers of β-Globin Gene Mutation Facilitates Genetic Counseling in β-Thalassemia: A Cross-Sectional Study in Kerman Province, Iran

BACKGROUND: β-thalassemia is characterized by reduced synthesis of the hemoglobin beta chain that results in microcytic hypochromic anemia and reduced amounts of hemoglobin A (HbA) on hemoglobin analysis. β-thalassemias are caused by mutations in the β-globin gene, inherited in an autosomal recessiv...

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Publicat a:Iran J Public Health
Autors principals: SALEH-GOHARI, Nasrollah, SAEIDI, Kolsoum, ZIAADINI-DASHTKHAKI, Sima
Format: Artigo
Idioma:Inglês
Publicat: Tehran University of Medical Sciences 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7283172/
https://ncbi.nlm.nih.gov/pubmed/32548060
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