Brain-age in midlife is associated with accelerated biological aging and cognitive decline in a longitudinal birth cohort

An individual’s brainAGE is the difference between chronological age and age predicted from machine-learning models of brain-imaging data. BrainAGE has been proposed as a biomarker of age-related deterioration of the brain. Having an older brainAGE has been linked to Alzheimer’s, dementia, and morta...

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Udgivet i:Mol Psychiatry
Main Authors: Elliott, Maxwell L., Belsky, Daniel W., Knodt, Annchen R., Ireland, David, Melzer, Tracy R., Poulton, Richie, Ramrakha, Sandhya, Caspi, Avshalom, Moffitt, Terrie E., Hariri, Ahmad R.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7282987/
https://ncbi.nlm.nih.gov/pubmed/31822815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41380-019-0626-7
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