Gene-based analyses of the maternal genome implicate maternal effect genes as risk factors for conotruncal heart defects

Congenital heart defects (CHDs) affect approximately 1% of newborns. Epidemiological studies have identified several genetically-mediated maternal phenotypes (e.g., pregestational diabetes, chronic hypertension) that are associated with the risk of CHDs in offspring. However, the role of the materna...

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Publicado en:PLoS One
Autores principales: Sewda, Anshuman, Agopian, A. J., Goldmuntz, Elizabeth, Hakonarson, Hakon, Morrow, Bernice E., Musfee, Fadi, Taylor, Deanne, Mitchell, Laura E.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2020
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7282656/
https://ncbi.nlm.nih.gov/pubmed/32516339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0234357
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