Clinical application of the AUC-guided dosage adjustment of docetaxel-based chemotherapy for patients with solid tumours: a single centre, prospective and randomised control study

BACKGROUND: Docetaxel (DTX) is a widely used anti-tumour drug, and its dosage is solely determined by body surface area (BSA). Adverse events, such as neutropenia or unsatisfied efficacy, likely occur because of differences in the pharmacokinetics (PK) and pharmacodynamics of patients. Thus, a feasi...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Sun, Ning, Shen, Bo, Zhu, Jiali, Zhang, Xiaomei, Zhu, Huayun, Liang, Geyu, Yang, Deliang, Lu, Jianwei, Zhang, Yan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7282138/
https://ncbi.nlm.nih.gov/pubmed/32513288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-020-02394-w
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