Bacteroides thetaiotaomicron-derived outer membrane vesicles promote regulatory dendritic cell responses in health but not in inflammatory bowel disease

BACKGROUND: Bacteroides thetaiotaomicron (Bt) is a prominent member of the human intestinal microbiota that, like all gram-negative bacteria, naturally generates nanosized outer membrane vesicles (OMVs) which bud off from the cell surface. Importantly, OMVs can cross the intestinal epithelial barrie...

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Bibliografiske detaljer
Udgivet i:Microbiome
Main Authors: Durant, Lydia, Stentz, Régis, Noble, Alistair, Brooks, Johanne, Gicheva, Nadezhda, Reddi, Durga, O’Connor, Matthew J., Hoyles, Lesley, McCartney, Anne L., Man, Ripple, Pring, E. Tobias, Dilke, Stella, Hendy, Philip, Segal, Jonathan P., Lim, Dennis N. F., Misra, Ravi, Hart, Ailsa L., Arebi, Naila, Carding, Simon R., Knight, Stella C.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7282036/
https://ncbi.nlm.nih.gov/pubmed/32513301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40168-020-00868-z
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