Rosuvastatin protects against endothelial cell apoptosis in vitro and alleviates atherosclerosis in ApoE(-/-) mice by suppressing endoplasmic reticulum stress

The development of abnormal lipid-induced atherosclerosis is initiated with endothelial cell apoptosis. Vascular endothelial cells possess highly developed endoplasmic reticulum (ER), which is involved in lipid metabolism, indicating that ER stress may contribute chiefly to the induction of endothel...

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Publicado en:Exp Ther Med
Autores principales: Geng, Jianan, Xu, Huali, Fu, Wenwen, Yu, Xiaofeng, Xu, Guoliang, Cao, Hongyan, Lin, Guangzhu, Sui, Dayun
Formato: Artigo
Lenguaje:Inglês
Publicado: D.A. Spandidos 2020
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7282009/
https://ncbi.nlm.nih.gov/pubmed/32537013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2020.8733
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