Phylogenetic reconstruction of breast cancer reveals two routes of metastatic dissemination associated with distinct clinical outcome

BACKGROUND: In breast cancer (BC), axillary lymph node (ALN) involvement is one of the strongest adverse prognostic factors. However, it is unclear whether loco-regional lymph node deposits are effectively the root of secondary metastases or only an indicator of competence of the primary tumour to s...

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Bibliografski detalji
Izdano u:EBioMedicine
Glavni autori: Venet, David, Fimereli, Danai, Rothé, Françoise, Boeckx, Bram, Maetens, Marion, Majjaj, Samira, Rouas, Ghizlane, Capra, Maria, Bonizzi, Giuseppina, Contaldo, Federica, Galant, Christine, Piccart, Martine, Pruneri, Giancarlo, Larsimont, Denis, Lambrechts, Diether, Desmedt, Christine, Sotiriou, Christos
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2020
Teme:
Research paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7281848/
https://ncbi.nlm.nih.gov/pubmed/32512508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.102793
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