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MicroRNA Regulation of the Small Rho GTPase Regulators—Complexities and Opportunities in Targeting Cancer Metastasis

The small Rho GTPases regulate important cellular processes that affect cancer metastasis, such as cell survival and proliferation, actin dynamics, adhesion, migration, invasion and transcriptional activation. The Rho GTPases function as molecular switches cycling between an active GTP-bound and ina...

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Bibliographic Details
Published in:Cancers (Basel)
Main Authors: Humphries, Brock A., Wang, Zhishan, Yang, Chengfeng
Format: Artigo
Language:Inglês
Published: MDPI 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7281527/
https://ncbi.nlm.nih.gov/pubmed/32353968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12051092
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