Contribution of Relapse-Independent Progression vs Relapse-Associated Worsening to Overall Confirmed Disability Accumulation in Typical Relapsing Multiple Sclerosis in a Pooled Analysis of 2 Randomized Clinical Trials

IMPORTANCE: Accumulation of disability in multiple sclerosis may occur as relapse-associated worsening (RAW) or steady progression independent of relapse activity (PIRA), with PIRA regarded as a feature of primary and secondary progressive multiple sclerosis. OBJECTIVE: To investigate the contributi...

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Foilsithe in:JAMA Neurol
Main Authors: Kappos, Ludwig, Wolinsky, Jerry S., Giovannoni, Gavin, Arnold, Douglas L., Wang, Qing, Bernasconi, Corrado, Model, Fabian, Koendgen, Harold, Manfrini, Marianna, Belachew, Shibeshih, Hauser, Stephen L.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Medical Association 2020
Ábhair:
Original Investigation
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7281382/
https://ncbi.nlm.nih.gov/pubmed/32511687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2020.1568
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