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Spectrum of Germline BRCA1 and BRCA2 Variants Identified in 2351 Ovarian and Breast Cancer Patients Referring to a Reference Cancer Hospital of Rome

Pathogenic variants (PVs) carriers in BRCA1 or BRCA2 are associated with an elevated lifetime risk of developing breast cancer (BC) and/or ovarian cancer (OC). The prevalence of BRCA1 and BRCA2 germline alterations is extremely variable among different ethnic groups. Particularly, the rate of varian...

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Bibliografiska uppgifter
I publikationen:Cancers (Basel)
Huvudupphovsmän: Santonocito, Concetta, Rizza, Roberta, Paris, Ida, De Marchis, Laura, Paolillo, Carmela, Tiberi, Giordana, Scambia, Giovanni, Capoluongo, Ettore
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7281099/
https://ncbi.nlm.nih.gov/pubmed/32438681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12051286
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