Adjuvant doxycycline to enhance anti-amyloid effects: Results from the dual phase 2 trial

BACKGROUND: Although, doxycycline use is associated with improved outcomes in amyloidosis in retrospective studies, evidence from clinical trials is limited. METHODS: This phase 2 trial of doxycycline (clinicaltrials.gov: NCT02207556) in newly diagnosed light chain (AL) amyloidosis enrolled 25 patie...

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Dettagli Bibliografici
Pubblicato in:EClinicalMedicine
Autori principali: D'Souza, Anita, Szabo, Aniko, Flynn, Kathryn E., Dhakal, Binod, Chhabra, Saurabh, Pasquini, Marcelo C., Weihrauch, Dorothee, Hari, Parameswaran N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2020
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Research paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7280748/
https://ncbi.nlm.nih.gov/pubmed/32529175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eclinm.2020.100361
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