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Interplay Between the IL-33/ST2 Axis and Bone Marrow ILC2s in Protease Allergen-Induced IL-5-Dependent Eosinophilia

Background: Eosinophils develop from CD34(+) progenitor cells in the bone marrow under the influence of interleukin (IL)-5. Several cell types produce IL-5, including type 2 innate lymphoid cells (ILC2s). The alarmin cytokine IL-33 is known to activate ILC2s in mucosal tissues, but little is known a...

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Vydáno v:Front Immunol
Hlavní autoři: Boberg, Emma, Johansson, Kristina, Malmhäll, Carina, Calvén, Jenny, Weidner, Julie, Rådinger, Madeleine
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7280539/
https://ncbi.nlm.nih.gov/pubmed/32582171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01058
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