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3-Amidinophenylalanine-derived matriptase inhibitors can modulate hepcidin production in vitro
Matriptase-2 (MT-2) is a type II transmembrane serine protease and predominantly attached to the surface of hepatocytes. MT-2 decreases the production of hepcidin, a key regulator of iron homeostasis. In this study, the effects of four 3-amidinophenylalanine-derived combined matriptase-1/matriptase-...
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| Publicado en: | Naunyn Schmiedebergs Arch Pharmacol |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Springer Berlin Heidelberg
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7280348/ https://ncbi.nlm.nih.gov/pubmed/31659405 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00210-019-01743-x |
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