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Synergistic gene editing in human iPS cells via cell cycle and DNA repair modulation
Precise gene editing aims at generating single-nucleotide modifications to correct or model human disease. However, precision editing with nucleases such as CRIPSR-Cas9 has seen limited success due to poor efficiency and limited practicality. Here, we establish a fluorescent DNA repair assay in huma...
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| 發表在: | Nat Commun |
|---|---|
| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group UK
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7280248/ https://ncbi.nlm.nih.gov/pubmed/32513994 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16643-5 |
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