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The monoclonal antibody Ca37, developed against Candida albicans alcohol dehydrogenase, inhibits the yeast in vitro and in vivo

Candida albicans is a commensal yeast able to cause life threatening invasive infections particularly in immunocompromised patients. Despite the availability of antifungal treatments, mortality rates are still unacceptably high and drug resistance is increasing. We, therefore, generated the Ca37 mon...

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Опубликовано в: :Sci Rep
Главные авторы: Antoran, Aitziber, Aparicio-Fernandez, Leire, Pellon, Aize, Buldain, Idoia, Martin-Souto, Leire, Rementeria, Aitor, Ghannoum, Mahmoud A., Fuchs, Beth Burgwyn, Mylonakis, Eleftherios, Hernando, Fernando L., Ramirez-Garcia, Andoni
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7280234/
https://ncbi.nlm.nih.gov/pubmed/32514067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-65859-4
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