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Comparison of the Efficacy of EGFR Tyrosine Kinase Inhibitors Erlotinib and Low-dose Osimertinib on a PC-9-GFP EGFR Mutant Non-small-cell Lung Cancer Growing in the Brain of Nude Mice

Background/Aim: Brain metastases are found in approximately 30% of patients with epidermal-growth-factor receptor (EGFR) mutant non-small cell lung cancer (NSCLC). We compared the efficacy of two EGFR-tyrosine kinase inhibitors (TKIs), erlotinib and osimertinib on a PC-9-GFP EGFR mutant NSCLC growin...

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Publicat a:In Vivo
Autors principals: KATSUYA, YUKI, MIYAKE, KENTARO, HIGUCHI, TAKASHI, OSHIRO, HIROMICHI, SUGISAWA, NORIHIKO, RAM SINGH, SHREE, GOTO, YASUSHI, ZHAO, MING, HOFFMAN, ROBERT M.
Format: Artigo
Idioma:Inglês
Publicat: International Institute of Anticancer Research 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7279826/
https://ncbi.nlm.nih.gov/pubmed/32354888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21873/invivo.11871
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