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High-Capacity Adenoviral Vectors: Expanding the Scope of Gene Therapy

The adaptation of adenoviruses as gene delivery tools has resulted in the development of high-capacity adenoviral vectors (HC-AdVs), also known, helper-dependent or “gutless”. Compared with earlier generations (E1/E3-deleted vectors), HC-AdVs retain relevant features such as genetic stability, remar...

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Библиографические подробности
Опубликовано в: :Int J Mol Sci
Главные авторы: Ricobaraza, Ana, Gonzalez-Aparicio, Manuela, Mora-Jimenez, Lucia, Lumbreras, Sara, Hernandez-Alcoceba, Ruben
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7279171/
https://ncbi.nlm.nih.gov/pubmed/32455640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21103643
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